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Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure
BACKGROUND: Epidemiological studies have found that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with increased risk for neural tube defects (NTDs). Aberrant DNA methylation, excessive apoptosis, and oxidative stress have been implied as the mechanism underlying the ass...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505285/ https://www.ncbi.nlm.nih.gov/pubmed/31064411 http://dx.doi.org/10.1186/s13148-019-0673-6 |