Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure

BACKGROUND: Epidemiological studies have found that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with increased risk for neural tube defects (NTDs). Aberrant DNA methylation, excessive apoptosis, and oxidative stress have been implied as the mechanism underlying the ass...

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Detalles Bibliográficos
Autores principales: Huang, Yun, Ren, Aiguo, Wang, Linlin, Jin, Lei, Lin, Shanshan, Li, Zhiwen, McDonald, Jasmine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505285/
https://www.ncbi.nlm.nih.gov/pubmed/31064411
http://dx.doi.org/10.1186/s13148-019-0673-6

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