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scNPF: an integrative framework assisted by network propagation and network fusion for preprocessing of single-cell RNA-seq data
BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) is fast becoming a powerful tool for profiling genome-scale transcriptomes of individual cells and capturing transcriptome-wide cell-to-cell variability. However, scRNA-seq technologies suffer from high levels of technical noise and variability, hin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505295/ https://www.ncbi.nlm.nih.gov/pubmed/31068142 http://dx.doi.org/10.1186/s12864-019-5747-5 |