TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

BACKGROUND: Low frequency coding variants in TREM2 are associated with Alzheimer disease (AD) risk and cerebrospinal fluid (CSF) TREM2 protein levels are different between AD cases and controls. Similarly, TREM2 risk variant carriers also exhibit differential CSF TREM2 levels. TREM2 has three differ...

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Detalles Bibliográficos
Autores principales: Del-Aguila, Jorge L., Benitez, Bruno A., Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A., Budde, John P., Farias, Fabiana H. G., Fernández, Maria Victoria, Ibanez, Laura, Jiang, Shan, Perrin, Richard J., Cairns, Nigel J., Morris, John C., Harari, Oscar, Cruchaga, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505298/
https://www.ncbi.nlm.nih.gov/pubmed/31068200
http://dx.doi.org/10.1186/s13024-019-0319-3

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