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Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker

Chloral hydrate (CH) poisoning is not commonly seen in the emergency department. CH is a commonly prescribed sedative agent for various day care procedures despite its toxic profile even when other safe sedative medications are available. We report a case of CH poisoning that manifested with neuroto...

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Detalles Bibliográficos
Autores principales: Shakeer, Shaik Karimulla, Kalapati, Babji, Al Abri, Suad Abdullah, Al Busaidi, Mujahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OMJ 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505342/
https://www.ncbi.nlm.nih.gov/pubmed/31110633
http://dx.doi.org/10.5001/omj.2019.46
Descripción
Sumario:Chloral hydrate (CH) poisoning is not commonly seen in the emergency department. CH is a commonly prescribed sedative agent for various day care procedures despite its toxic profile even when other safe sedative medications are available. We report a case of CH poisoning that manifested with neurotoxicity followed by cardiotoxicity leading to cardiac arrest. With a high index of suspicion and proper management, our patient was discharged with normal neurological outcome. In this case report, we discuss CH poisoning and toxicity with highlights on specific intervention including β-blockers. CH induced arrhythmias have been reported to be refractory to the standard antiarrhythmic medications and respond well to β-blockers.