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Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker

Chloral hydrate (CH) poisoning is not commonly seen in the emergency department. CH is a commonly prescribed sedative agent for various day care procedures despite its toxic profile even when other safe sedative medications are available. We report a case of CH poisoning that manifested with neuroto...

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Detalles Bibliográficos
Autores principales: Shakeer, Shaik Karimulla, Kalapati, Babji, Al Abri, Suad Abdullah, Al Busaidi, Mujahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OMJ 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505342/
https://www.ncbi.nlm.nih.gov/pubmed/31110633
http://dx.doi.org/10.5001/omj.2019.46
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author Shakeer, Shaik Karimulla
Kalapati, Babji
Al Abri, Suad Abdullah
Al Busaidi, Mujahid
author_facet Shakeer, Shaik Karimulla
Kalapati, Babji
Al Abri, Suad Abdullah
Al Busaidi, Mujahid
author_sort Shakeer, Shaik Karimulla
collection PubMed
description Chloral hydrate (CH) poisoning is not commonly seen in the emergency department. CH is a commonly prescribed sedative agent for various day care procedures despite its toxic profile even when other safe sedative medications are available. We report a case of CH poisoning that manifested with neurotoxicity followed by cardiotoxicity leading to cardiac arrest. With a high index of suspicion and proper management, our patient was discharged with normal neurological outcome. In this case report, we discuss CH poisoning and toxicity with highlights on specific intervention including β-blockers. CH induced arrhythmias have been reported to be refractory to the standard antiarrhythmic medications and respond well to β-blockers.
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spelling pubmed-65053422019-05-20 Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker Shakeer, Shaik Karimulla Kalapati, Babji Al Abri, Suad Abdullah Al Busaidi, Mujahid Oman Med J Case Report Chloral hydrate (CH) poisoning is not commonly seen in the emergency department. CH is a commonly prescribed sedative agent for various day care procedures despite its toxic profile even when other safe sedative medications are available. We report a case of CH poisoning that manifested with neurotoxicity followed by cardiotoxicity leading to cardiac arrest. With a high index of suspicion and proper management, our patient was discharged with normal neurological outcome. In this case report, we discuss CH poisoning and toxicity with highlights on specific intervention including β-blockers. CH induced arrhythmias have been reported to be refractory to the standard antiarrhythmic medications and respond well to β-blockers. OMJ 2019-05 /pmc/articles/PMC6505342/ /pubmed/31110633 http://dx.doi.org/10.5001/omj.2019.46 Text en The OMJ is Published Bimonthly and Copyrighted 2019 by the OMSB. This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). ( https://creativecommons.org/licenses/by-nc/4.0/).
spellingShingle Case Report
Shakeer, Shaik Karimulla
Kalapati, Babji
Al Abri, Suad Abdullah
Al Busaidi, Mujahid
Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker
title Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker
title_full Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker
title_fullStr Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker
title_full_unstemmed Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker
title_short Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker
title_sort chloral hydrate overdose survived after cardiac arrest with excellent response to intravenous β-blocker
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505342/
https://www.ncbi.nlm.nih.gov/pubmed/31110633
http://dx.doi.org/10.5001/omj.2019.46
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