One hundred years of Drosophila cancer research: no longer in solitude

When Mary Stark first described the presence of tumours in the fruit fly Drosophila melanogaster in 1918, would she ever have imagined that flies would become an invaluable organism for modelling and understanding oncogenesis? And if so, would she have expected it to take 100 years for this model to...

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Detalles Bibliográficos
Autor principal: Villegas, Santiago Nahuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Special Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505481/
https://www.ncbi.nlm.nih.gov/pubmed/30952627
http://dx.doi.org/10.1242/dmm.039032
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author Villegas, Santiago Nahuel
author_facet Villegas, Santiago Nahuel
author_sort Villegas, Santiago Nahuel
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description When Mary Stark first described the presence of tumours in the fruit fly Drosophila melanogaster in 1918, would she ever have imagined that flies would become an invaluable organism for modelling and understanding oncogenesis? And if so, would she have expected it to take 100 years for this model to be fully accredited? This Special Article summarises the efforts and achievements of Drosophilists to establish the fly as a valid model in cancer research through different scientific periods.
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spelling pubmed-65054812019-05-09 One hundred years of Drosophila cancer research: no longer in solitude Villegas, Santiago Nahuel Dis Model Mech Special Article When Mary Stark first described the presence of tumours in the fruit fly Drosophila melanogaster in 1918, would she ever have imagined that flies would become an invaluable organism for modelling and understanding oncogenesis? And if so, would she have expected it to take 100 years for this model to be fully accredited? This Special Article summarises the efforts and achievements of Drosophilists to establish the fly as a valid model in cancer research through different scientific periods. The Company of Biologists Ltd 2019-04-01 2019-04-01 /pmc/articles/PMC6505481/ /pubmed/30952627 http://dx.doi.org/10.1242/dmm.039032 Text en © 2019. Published by The Company of Biologists Ltd http://creativecommons.org/licenses/by/4.0This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Special Article
Villegas, Santiago Nahuel
One hundred years of Drosophila cancer research: no longer in solitude
title One hundred years of Drosophila cancer research: no longer in solitude
title_full One hundred years of Drosophila cancer research: no longer in solitude
title_fullStr One hundred years of Drosophila cancer research: no longer in solitude
title_full_unstemmed One hundred years of Drosophila cancer research: no longer in solitude
title_short One hundred years of Drosophila cancer research: no longer in solitude
title_sort one hundred years of drosophila cancer research: no longer in solitude
topic Special Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505481/
https://www.ncbi.nlm.nih.gov/pubmed/30952627
http://dx.doi.org/10.1242/dmm.039032
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