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Modeling Alzheimer’s Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation

Alzheimer’s disease (AD), probably caused by abnormal accumulation of β-amyloid (Aβ) and aberrant phosphorylation of tau, is the most common cause of dementia among older people. Generation of patient-specific neurons by induced pluripotent stem cell (iPSC) technology facilitates exploration of the...

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Detalles Bibliográficos
Autores principales:	Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen, Huang, Ching-Chang, Lin, Jia-Li, Chen, Yi-Jing, Wei, Pei-Chi, Lo, Yen-Shi, Yao, Chin-Fa, Kuo, Ming-Wei, Chen, Chiung-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505505/ https://www.ncbi.nlm.nih.gov/pubmed/30238389 http://dx.doi.org/10.1007/s12035-018-1336-x

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