Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

Rapid antidepressant effects of ketamine become most evident when its psychotomimetic effects subside, but the neurobiological basis of this “lag” remains unclear. Laughing gas (N(2)O), another NMDA-R (N-methyl-d-aspartate receptor) blocker, has been reported to bring antidepressant effects rapidly...

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Detalles Bibliográficos
Autores principales: Kohtala, Samuel, Theilmann, Wiebke, Rosenholm, Marko, Penna, Leena, Karabulut, Gulsum, Uusitalo, Salla, Järventausta, Kaija, Yli-Hankala, Arvi, Yalcin, Ipek, Matsui, Nobuaki, Wigren, Henna-Kaisa, Rantamäki, Tomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505519/
https://www.ncbi.nlm.nih.gov/pubmed/30288695
http://dx.doi.org/10.1007/s12035-018-1364-6

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