Chromosomes missegregated into micronuclei contribute to chromosomal instability by missegregating at the next division

Micronuclei (MNi) are extranuclear DNA-containing structures that form upon mitotic exit from unsegregated chromosome fragments or anaphase lagging (whole) chromosomes (LCs). MNi formed from whole chromosomes are of particular interest because LCs are observed in both cancer and non-cancer cells, an...

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Detalles Bibliográficos
Autores principales: He, Bin, Gnawali, Nisha, Hinman, Albert W., Mattingly, Aaron J., Osimani, Alyssa, Cimini, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper: Chromosome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505630/
https://www.ncbi.nlm.nih.gov/pubmed/31105868
http://dx.doi.org/10.18632/oncotarget.26853

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