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Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling

BACKGROUND: One of the key steps in generating three-dimensional (3D) printed models in medicine is segmentation of radiologic imaging. The software tools used for segmentation may be automated, semi-automated, or manual which rely on differences in material density, attenuation characteristics, and...

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Autores principales: Kikano, Elias, Grosse Hokamp, Nils, Ciancibello, Leslie, Ramaiya, Nikhil, Kosmas, Christos, Gupta, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505638/
https://www.ncbi.nlm.nih.gov/pubmed/30659415
http://dx.doi.org/10.1186/s41205-019-0038-y
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author Kikano, Elias
Grosse Hokamp, Nils
Ciancibello, Leslie
Ramaiya, Nikhil
Kosmas, Christos
Gupta, Amit
author_facet Kikano, Elias
Grosse Hokamp, Nils
Ciancibello, Leslie
Ramaiya, Nikhil
Kosmas, Christos
Gupta, Amit
author_sort Kikano, Elias
collection PubMed
description BACKGROUND: One of the key steps in generating three-dimensional (3D) printed models in medicine is segmentation of radiologic imaging. The software tools used for segmentation may be automated, semi-automated, or manual which rely on differences in material density, attenuation characteristics, and/or advanced software algorithms. Spectral Detector Computed Tomography (SDCT) is a form of dual energy computed tomography that works at the detector level to generate virtual monoenergetic images (VMI) at different energies/ kilo-electron volts (keV). These VMI have varying contrast and attenuation characteristics relative to material density. The purpose of this pilot project is to explore the use of VMI in segmentation for medical 3D printing in four separate clinical scenarios. Cases were retrospectively selected based on varying complexity, value of spectral data, and across multiple clinical disciplines (Vascular, Cardiology, Oncology, and Orthopedic). RESULTS: In all four clinical cases presented, the segmentation process was qualitatively reported as easier, faster, and increased the operator’s confidence in obtaining accurate anatomy. All cases demonstrated a significant difference in the calculated Hounsfield Units between conventional and VMI data at the level of targeted segmentation anatomy. Two cases would not have been feasible for segmentation and 3D printing using conventional images only. VMI data significantly reduced conventional CT artifacts in one of the cases. CONCLUSION: Utilization of VMI from SDCT can improve and assist the segmentation of target anatomy for medical 3D printing by enhancing material contrast and decreasing CT artifact. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s41205-019-0038-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-65056382019-08-02 Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling Kikano, Elias Grosse Hokamp, Nils Ciancibello, Leslie Ramaiya, Nikhil Kosmas, Christos Gupta, Amit 3D Print Med Research BACKGROUND: One of the key steps in generating three-dimensional (3D) printed models in medicine is segmentation of radiologic imaging. The software tools used for segmentation may be automated, semi-automated, or manual which rely on differences in material density, attenuation characteristics, and/or advanced software algorithms. Spectral Detector Computed Tomography (SDCT) is a form of dual energy computed tomography that works at the detector level to generate virtual monoenergetic images (VMI) at different energies/ kilo-electron volts (keV). These VMI have varying contrast and attenuation characteristics relative to material density. The purpose of this pilot project is to explore the use of VMI in segmentation for medical 3D printing in four separate clinical scenarios. Cases were retrospectively selected based on varying complexity, value of spectral data, and across multiple clinical disciplines (Vascular, Cardiology, Oncology, and Orthopedic). RESULTS: In all four clinical cases presented, the segmentation process was qualitatively reported as easier, faster, and increased the operator’s confidence in obtaining accurate anatomy. All cases demonstrated a significant difference in the calculated Hounsfield Units between conventional and VMI data at the level of targeted segmentation anatomy. Two cases would not have been feasible for segmentation and 3D printing using conventional images only. VMI data significantly reduced conventional CT artifacts in one of the cases. CONCLUSION: Utilization of VMI from SDCT can improve and assist the segmentation of target anatomy for medical 3D printing by enhancing material contrast and decreasing CT artifact. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s41205-019-0038-y) contains supplementary material, which is available to authorized users. Springer International Publishing 2019-01-18 /pmc/articles/PMC6505638/ /pubmed/30659415 http://dx.doi.org/10.1186/s41205-019-0038-y Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research
Kikano, Elias
Grosse Hokamp, Nils
Ciancibello, Leslie
Ramaiya, Nikhil
Kosmas, Christos
Gupta, Amit
Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling
title Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling
title_full Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling
title_fullStr Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling
title_full_unstemmed Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling
title_short Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling
title_sort utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3d printing and modeling
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505638/
https://www.ncbi.nlm.nih.gov/pubmed/30659415
http://dx.doi.org/10.1186/s41205-019-0038-y
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