Structure of the RecQ C-terminal Domain of Human Bloom Syndrome Protein

Bloom syndrome is a rare genetic disorder characterized by genomic instability and cancer predisposition. The disease is caused by mutations of the Bloom syndrome protein (BLM). Here we report the crystal structure of a RecQ C-terminal (RQC) domain from human BLM. The structure reveals three novel f...

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Detalles Bibliográficos
Autores principales: Kim, Sun-Yong, Hakoshima, Toshio, Kitano, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505963/
https://www.ncbi.nlm.nih.gov/pubmed/24257077
http://dx.doi.org/10.1038/srep03294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505963/
https://www.ncbi.nlm.nih.gov/pubmed/24257077
http://dx.doi.org/10.1038/srep03294

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