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HIF-1α regulates IL-1β and IL-17 in sarcoidosis

Sarcoidosis is a complex systemic granulomatous disease of unknown etiology characterized by the presence of activated macrophages and Th1/Th17 effector cells. Data mining of our RNA-Seq analysis of CD14(+)monocytes showed enrichment for metabolic and hypoxia inducible factor (HIF) pathways in sarco...

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Detalles Bibliográficos
Autores principales:	Talreja, Jaya, Talwar, Harvinder, Bauerfeld, Christian, Grossman, Lawrence I, Zhang, Kezhong, Tranchida, Paul, Samavati, Lobelia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Human Biology and Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506207/ https://www.ncbi.nlm.nih.gov/pubmed/30946009 http://dx.doi.org/10.7554/eLife.44519

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