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Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers

Beta-catenin (i.e., canonical Wnt) signaling controls CNS angiogenesis and the blood-brain and blood-retina barriers. To explore the role of the Discs large/membrane-associated guanylate kinase (Dlg/MAGUK) family of scaffolding proteins in beta-catenin signaling, we studied vascular endothelial cell...

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Detalles Bibliográficos
Autores principales: Cho, Chris, Wang, Yanshu, Smallwood, Philip M, Williams, John, Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506210/
https://www.ncbi.nlm.nih.gov/pubmed/31066677
http://dx.doi.org/10.7554/eLife.45542