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Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time
In mammals, endogenous circadian clocks sense and respond to daily feeding and lighting cues, adjusting internal ∼24 h rhythms to resonate with, and anticipate, external cycles of day and night. The mechanism underlying circadian entrainment to feeding time is critical for understanding why mistimed...
Autores principales: | Crosby, Priya, Hamnett, Ryan, Putker, Marrit, Hoyle, Nathaniel P., Reed, Martin, Karam, Carolyn J., Maywood, Elizabeth S., Stangherlin, Alessandra, Chesham, Johanna E., Hayter, Edward A., Rosenbrier-Ribeiro, Lyn, Newham, Peter, Clevers, Hans, Bechtold, David A., O’Neill, John S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506277/ https://www.ncbi.nlm.nih.gov/pubmed/31030999 http://dx.doi.org/10.1016/j.cell.2019.02.017 |
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