Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole

Fungal keratitis by Phoma species is rare, and little information has been accumulated. We report a case of keratitis caused by Didymella gardeniae, formerly known as P. gardeniae. The patient had a history of stromal herpetic keratitis and had been treated with long-term topical betamethasone. He d...

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Autores principales: Miyakubo, Tomoko, Todokoro, Daisuke, Makimura, Koichi, Akiyama, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506558/
https://www.ncbi.nlm.nih.gov/pubmed/31080716
http://dx.doi.org/10.1016/j.mmcr.2019.04.006
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author Miyakubo, Tomoko
Todokoro, Daisuke
Makimura, Koichi
Akiyama, Hideo
author_facet Miyakubo, Tomoko
Todokoro, Daisuke
Makimura, Koichi
Akiyama, Hideo
author_sort Miyakubo, Tomoko
collection PubMed
description Fungal keratitis by Phoma species is rare, and little information has been accumulated. We report a case of keratitis caused by Didymella gardeniae, formerly known as P. gardeniae. The patient had a history of stromal herpetic keratitis and had been treated with long-term topical betamethasone. He developed infectious keratitis in the left eye, with the causative fungus identified by ribosomal DNA sequencing. Combination treatment with topical voriconazole and miconazole proved effective.
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spelling pubmed-65065582019-05-10 Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole Miyakubo, Tomoko Todokoro, Daisuke Makimura, Koichi Akiyama, Hideo Med Mycol Case Rep Case Report Fungal keratitis by Phoma species is rare, and little information has been accumulated. We report a case of keratitis caused by Didymella gardeniae, formerly known as P. gardeniae. The patient had a history of stromal herpetic keratitis and had been treated with long-term topical betamethasone. He developed infectious keratitis in the left eye, with the causative fungus identified by ribosomal DNA sequencing. Combination treatment with topical voriconazole and miconazole proved effective. Elsevier 2019-04-27 /pmc/articles/PMC6506558/ /pubmed/31080716 http://dx.doi.org/10.1016/j.mmcr.2019.04.006 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Miyakubo, Tomoko
Todokoro, Daisuke
Makimura, Koichi
Akiyama, Hideo
Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole
title Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole
title_full Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole
title_fullStr Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole
title_full_unstemmed Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole
title_short Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole
title_sort fungal keratitis caused by didymella gardeniae (formerly phoma gardeniae) successfully treated with topical voriconazole and miconazole
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506558/
https://www.ncbi.nlm.nih.gov/pubmed/31080716
http://dx.doi.org/10.1016/j.mmcr.2019.04.006
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