Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation

B cell lymphoma-6 (BCL6) is highly expressed in germinal center B cells, but how its expression is maintained is still not completely clear. Aryl hydrocarbon receptor interacting protein (AIP) is a co-chaperone of heat shock protein 90. Deletion of Aip in B cells decreased BCL6 expression, reducing...

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Detalles Bibliográficos
Autores principales: Sun, Dijue, Stopka-Farooqui, Urszula, Barry, Sayka, Aksoy, Ezra, Parsonage, Gregory, Vossenkämper, Anna, Capasso, Melania, Wan, Xinyu, Norris, Sherine, Marshall, Jennifer L., Clear, Andrew, Gribben, John, MacDonald, Thomas T., Buckley, Christopher D., Korbonits, Márta, Haworth, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506688/
https://www.ncbi.nlm.nih.gov/pubmed/31042473
http://dx.doi.org/10.1016/j.celrep.2019.04.014

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