IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors

Despite significant progress in annotating the genome with experimental methods, much of the regulatory noncoding genome remains poorly defined. Here we assert that regulatory elements may be characterized by leveraging local epigenomic signatures where specific transcription factors (TFs) are bound...

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Detalles Bibliográficos
Autores principales: Amariuta, Tiffany, Luo, Yang, Gazal, Steven, Davenport, Emma E., van de Geijn, Bryce, Ishigaki, Kazuyoshi, Westra, Harm-Jan, Teslovich, Nikola, Okada, Yukinori, Yamamoto, Kazuhiko, Price, Alkes L., Raychaudhuri, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506796/
https://www.ncbi.nlm.nih.gov/pubmed/31006511
http://dx.doi.org/10.1016/j.ajhg.2019.03.012

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