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Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K/AKT/FoxO1 pathway
BACKGROUND: Baicalin, which is isolated from Radix Scutellariae, possesses strong biological activities including an anti-inflammation property. Recent studies have shown that the anti-inflammatory effect of baicalin is linked to toll-like receptor 4 (TLR4), which participates in pathological change...
Autores principales: | Guo, Li-Ting, Wang, Si-Qi, Su, Jing, Xu, Li-Xing, Ji, Zhou-Ye, Zhang, Ru-Yi, Zhao, Qin-Wen, Ma, Zhan-Qiang, Deng, Xue-Yang, Ma, Shi-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507025/ https://www.ncbi.nlm.nih.gov/pubmed/31068207 http://dx.doi.org/10.1186/s12974-019-1474-8 |
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