A novel approach to determine two optimal cut-points of a continuous predictor with a U-shaped relationship to hazard ratio in survival data: simulation and application

BACKGROUND: In clinical and epidemiological researches, continuous predictors are often discretized into categorical variables for classification of patients. When the relationship between a continuous predictor and log relative hazards is U-shaped in survival data, there is a lack of a satisfying s...

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Detalles Bibliográficos
Autores principales: Chen, Yimin, Huang, Jialing, He, Xianying, Gao, Yongxiang, Mahara, Gehendra, Lin, Zhuochen, Zhang, Jinxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507062/
https://www.ncbi.nlm.nih.gov/pubmed/31072334
http://dx.doi.org/10.1186/s12874-019-0738-4

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