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Elastin‐Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease

BACKGROUND: Thoracic aortic aneurysm (TAA) and dissection (TAD) are characterized by progressive disorganization of the aortic wall matrix, including elastin, a highly immunogenic molecule. Whether acquired autoimmune responses can be detected in TAA/TAD patients who are smokers is unknown. The obje...

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Detalles Bibliográficos
Autores principales: Gu, Bon‐Hee, Choi, Justin C., Shen, Ying H., Song, Li‐Zhen, Scheurer, Michael E., Luong, Amber, Rodriguez, Antony, Woodruff, Prescott, Koth, Laura, Corry, David B., Kheradmand, Farrah, LeMaire, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507218/
https://www.ncbi.nlm.nih.gov/pubmed/30957625
http://dx.doi.org/10.1161/JAHA.118.011671