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Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog

An 11-year-old female spayed Maltese presented comatose, half an hour after vehicular trauma, and was treated for traumatic brain injury and pulmonary contusions. The dog developed severe hypernatremia within six hours of presentation, which responded poorly to the administration of five percent dex...

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Autores principales: Croton, Catriona, Purcell, Sarah, Schoep, Andrea, Haworth, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507253/
https://www.ncbi.nlm.nih.gov/pubmed/31179153
http://dx.doi.org/10.1155/2019/3563675
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author Croton, Catriona
Purcell, Sarah
Schoep, Andrea
Haworth, Mark
author_facet Croton, Catriona
Purcell, Sarah
Schoep, Andrea
Haworth, Mark
author_sort Croton, Catriona
collection PubMed
description An 11-year-old female spayed Maltese presented comatose, half an hour after vehicular trauma, and was treated for traumatic brain injury and pulmonary contusions. The dog developed severe hypernatremia within six hours of presentation, which responded poorly to the administration of five percent dextrose in water. As central diabetes insipidus was suspected, desmopressin was trialled and resolution of hypernatremia was achieved six days later. Transient trauma-induced central diabetes insipidus has been described previously in two dogs; in the first, serum sodium concentrations were evaluated three days after injury and the other developed hypernatremia seven days after injury. To the authors' knowledge, this is the first report of rapid onset, transient, and trauma-induced central diabetes insipidus in a dog that encompasses the complete clinical progression of the syndrome from shortly after injury through to resolution.
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spelling pubmed-65072532019-06-09 Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog Croton, Catriona Purcell, Sarah Schoep, Andrea Haworth, Mark Case Rep Vet Med Case Report An 11-year-old female spayed Maltese presented comatose, half an hour after vehicular trauma, and was treated for traumatic brain injury and pulmonary contusions. The dog developed severe hypernatremia within six hours of presentation, which responded poorly to the administration of five percent dextrose in water. As central diabetes insipidus was suspected, desmopressin was trialled and resolution of hypernatremia was achieved six days later. Transient trauma-induced central diabetes insipidus has been described previously in two dogs; in the first, serum sodium concentrations were evaluated three days after injury and the other developed hypernatremia seven days after injury. To the authors' knowledge, this is the first report of rapid onset, transient, and trauma-induced central diabetes insipidus in a dog that encompasses the complete clinical progression of the syndrome from shortly after injury through to resolution. Hindawi 2019-04-22 /pmc/articles/PMC6507253/ /pubmed/31179153 http://dx.doi.org/10.1155/2019/3563675 Text en Copyright © 2019 Catriona Croton et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Croton, Catriona
Purcell, Sarah
Schoep, Andrea
Haworth, Mark
Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog
title Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog
title_full Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog
title_fullStr Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog
title_full_unstemmed Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog
title_short Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog
title_sort successful treatment of transient central diabetes insipidus following traumatic brain injury in a dog
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507253/
https://www.ncbi.nlm.nih.gov/pubmed/31179153
http://dx.doi.org/10.1155/2019/3563675
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