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Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model

The inverse probability of treatment weighted (IPTW) estimator can be used to make causal inferences under two assumptions: (1) no unobserved confounders (ignorability) and (2) positive probability of treatment and of control at every level of the confounders (positivity), but is vulnerable to bias...

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Autores principales: Wang, Mary Ying-Fang, Tuss, Paul, Qi, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507518/
https://www.ncbi.nlm.nih.gov/pubmed/30877425
http://dx.doi.org/10.1007/s11336-018-09657-y
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author Wang, Mary Ying-Fang
Tuss, Paul
Qi, Lihong
author_facet Wang, Mary Ying-Fang
Tuss, Paul
Qi, Lihong
author_sort Wang, Mary Ying-Fang
collection PubMed
description The inverse probability of treatment weighted (IPTW) estimator can be used to make causal inferences under two assumptions: (1) no unobserved confounders (ignorability) and (2) positive probability of treatment and of control at every level of the confounders (positivity), but is vulnerable to bias if by chance, the proportion of the sample assigned to treatment, or proportion of control, is zero at certain levels of the confounders. We propose to deal with this sampling zero problem, also known as practical violation of the positivity assumption, in a setting where the observed confounder is cluster identity, i.e., treatment assignment is ignorable within clusters. Specifically, based on a random coefficient model assumed for the potential outcome, we augment the IPTW estimating function with the estimated potential outcomes of treatment (or of control) for clusters that have no observation of treatment (or control). If the cluster-specific potential outcomes are estimated correctly, the augmented estimating function can be shown to converge in expectation to zero and therefore yield consistent causal estimates. The proposed method can be implemented in the existing software, and it performs well in simulated data as well as with real-world data from a teacher preparation evaluation study. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11336-018-09657-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-65075182019-05-28 Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model Wang, Mary Ying-Fang Tuss, Paul Qi, Lihong Psychometrika Article The inverse probability of treatment weighted (IPTW) estimator can be used to make causal inferences under two assumptions: (1) no unobserved confounders (ignorability) and (2) positive probability of treatment and of control at every level of the confounders (positivity), but is vulnerable to bias if by chance, the proportion of the sample assigned to treatment, or proportion of control, is zero at certain levels of the confounders. We propose to deal with this sampling zero problem, also known as practical violation of the positivity assumption, in a setting where the observed confounder is cluster identity, i.e., treatment assignment is ignorable within clusters. Specifically, based on a random coefficient model assumed for the potential outcome, we augment the IPTW estimating function with the estimated potential outcomes of treatment (or of control) for clusters that have no observation of treatment (or control). If the cluster-specific potential outcomes are estimated correctly, the augmented estimating function can be shown to converge in expectation to zero and therefore yield consistent causal estimates. The proposed method can be implemented in the existing software, and it performs well in simulated data as well as with real-world data from a teacher preparation evaluation study. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11336-018-09657-y) contains supplementary material, which is available to authorized users. Springer US 2019-03-15 2019 /pmc/articles/PMC6507518/ /pubmed/30877425 http://dx.doi.org/10.1007/s11336-018-09657-y Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Article
Wang, Mary Ying-Fang
Tuss, Paul
Qi, Lihong
Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model
title Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model
title_full Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model
title_fullStr Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model
title_full_unstemmed Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model
title_short Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model
title_sort augmented weighted estimators dealing with practical positivity violation to causal inferences in a random coefficient model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507518/
https://www.ncbi.nlm.nih.gov/pubmed/30877425
http://dx.doi.org/10.1007/s11336-018-09657-y
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