Cargando…
Identification of potential therapeutic target genes in mouse mesangial cells associated with diabetic nephropathy using bioinformatics analysis
The aim of the present study was to identify genes under the effect of transforming growth factor-β (TGF-β1), high glucose (HG) and glucosamine (GlcN) in MES-13 mesangial cells and elucidate the molecular mechanisms of diabetic nephropathy (DN). The gene expression datasets GSE2557 and GSE2558 were...
Autores principales: | Mou, Xin, Zhou, Di Yi, Liu, Ying Hui, Liu, Kaiyuan, Zhou, Danyang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507521/ https://www.ncbi.nlm.nih.gov/pubmed/31105790 http://dx.doi.org/10.3892/etm.2019.7524 |
Ejemplares similares
-
A novel identified circular RNA, circ_0000491, aggravates the extracellular matrix of diabetic nephropathy glomerular mesangial cells through suppressing miR-101b by targeting TGFβRI
por: Mou, Xin, et al.
Publicado: (2020) -
Identification of C3 as a therapeutic target for diabetic nephropathy by bioinformatics analysis
por: Tang, ShuMei, et al.
Publicado: (2020) -
Identification of potential biomarkers and therapeutic targets for human IgA nephropathy and hypertensive nephropathy by bioinformatics analysis
por: Cui, Yingchun, et al.
Publicado: (2017) -
In silico prediction and validation of potential therapeutic genes in pancreatic β-cells associated with type 2 diabetes
por: Zhou, Di Yi, et al.
Publicado: (2020) -
Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation
por: Thomas, Haryana Y., et al.
Publicado: (2022)