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Cellular response upon proliferation in the presence of an active mitotic checkpoint

Eukaryotic cells treated with microtubule-targeting agents activate the spindle assembly checkpoint to arrest in mitosis and prevent chromosome mis-segregation. A fraction of mitotically arrested cells overcomes the block and proliferates even under persistent checkpoint-activating conditions. Here,...

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Detalles Bibliográficos
Autores principales: Corno, Andrea, Chiroli, Elena, Gross, Fridolin, Vernieri, Claudio, Matafora, Vittoria, Maffini, Stefano, Cosentino Lagomarsino, Marco, Bachi, Angela, Ciliberto, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507650/
https://www.ncbi.nlm.nih.gov/pubmed/31068378
http://dx.doi.org/10.26508/lsa.201900380