Monosegmental ALPPS: a long-term survival alternative to liver transplant in PRETEXT IV hepatoblastoma

A 3-year-old female was treated with neoadjuvant chemotherapy (NACT) for a PRETEXT IV hepatoblastoma. POST-TEXT IV findings merited a liver transplant (LT), but multiple limitations precluded it. The initial future liver remnant (FLR) was small (21.3%). Monosegment 6 ALPPS was a rational approach gi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruiz Figueroa, Eloy Francisco, Fernández-Placencia, Ramiro Manuel, Berrospi Espinoza, Francisco Enrique, Gomez, Henry F, Chávez Passiuri, Ivan Klever
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Innovation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507791/
https://www.ncbi.nlm.nih.gov/pubmed/31086654
http://dx.doi.org/10.1093/jscr/rjz144
_version_ 1783417057062158336
author Ruiz Figueroa, Eloy Francisco
Fernández-Placencia, Ramiro Manuel
Berrospi Espinoza, Francisco Enrique
Gomez, Henry F
Chávez Passiuri, Ivan Klever
author_facet Ruiz Figueroa, Eloy Francisco
Fernández-Placencia, Ramiro Manuel
Berrospi Espinoza, Francisco Enrique
Gomez, Henry F
Chávez Passiuri, Ivan Klever
author_sort Ruiz Figueroa, Eloy Francisco
collection PubMed
description A 3-year-old female was treated with neoadjuvant chemotherapy (NACT) for a PRETEXT IV hepatoblastoma. POST-TEXT IV findings merited a liver transplant (LT), but multiple limitations precluded it. The initial future liver remnant (FLR) was small (21.3%). Monosegment 6 ALPPS was a rational approach given that the inferior right hepatic vein (IRHV) provided adequate outflow. Therefore, the procedure was performed after parental informed consent. On PO15 of the first stage, FLR had reached 32.6% and then the second-stage was carried out. The patient was discharged on POD 31, and she is about to reach the 5-year disease-free survival milestone.
format Online
Article
Text
id pubmed-6507791
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-65077912019-05-13 Monosegmental ALPPS: a long-term survival alternative to liver transplant in PRETEXT IV hepatoblastoma Ruiz Figueroa, Eloy Francisco Fernández-Placencia, Ramiro Manuel Berrospi Espinoza, Francisco Enrique Gomez, Henry F Chávez Passiuri, Ivan Klever J Surg Case Rep Innovation A 3-year-old female was treated with neoadjuvant chemotherapy (NACT) for a PRETEXT IV hepatoblastoma. POST-TEXT IV findings merited a liver transplant (LT), but multiple limitations precluded it. The initial future liver remnant (FLR) was small (21.3%). Monosegment 6 ALPPS was a rational approach given that the inferior right hepatic vein (IRHV) provided adequate outflow. Therefore, the procedure was performed after parental informed consent. On PO15 of the first stage, FLR had reached 32.6% and then the second-stage was carried out. The patient was discharged on POD 31, and she is about to reach the 5-year disease-free survival milestone. Oxford University Press 2019-05-09 /pmc/articles/PMC6507791/ /pubmed/31086654 http://dx.doi.org/10.1093/jscr/rjz144 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2019. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Innovation
Ruiz Figueroa, Eloy Francisco
Fernández-Placencia, Ramiro Manuel
Berrospi Espinoza, Francisco Enrique
Gomez, Henry F
Chávez Passiuri, Ivan Klever
Monosegmental ALPPS: a long-term survival alternative to liver transplant in PRETEXT IV hepatoblastoma
title Monosegmental ALPPS: a long-term survival alternative to liver transplant in PRETEXT IV hepatoblastoma
title_full Monosegmental ALPPS: a long-term survival alternative to liver transplant in PRETEXT IV hepatoblastoma
title_fullStr Monosegmental ALPPS: a long-term survival alternative to liver transplant in PRETEXT IV hepatoblastoma
title_full_unstemmed Monosegmental ALPPS: a long-term survival alternative to liver transplant in PRETEXT IV hepatoblastoma
title_short Monosegmental ALPPS: a long-term survival alternative to liver transplant in PRETEXT IV hepatoblastoma
title_sort monosegmental alpps: a long-term survival alternative to liver transplant in pretext iv hepatoblastoma
topic Innovation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507791/
https://www.ncbi.nlm.nih.gov/pubmed/31086654
http://dx.doi.org/10.1093/jscr/rjz144
work_keys_str_mv AT ruizfigueroaeloyfrancisco monosegmentalalppsalongtermsurvivalalternativetolivertransplantinpretextivhepatoblastoma
AT fernandezplacenciaramiromanuel monosegmentalalppsalongtermsurvivalalternativetolivertransplantinpretextivhepatoblastoma
AT berrospiespinozafranciscoenrique monosegmentalalppsalongtermsurvivalalternativetolivertransplantinpretextivhepatoblastoma
AT gomezhenryf monosegmentalalppsalongtermsurvivalalternativetolivertransplantinpretextivhepatoblastoma
AT chavezpassiuriivanklever monosegmentalalppsalongtermsurvivalalternativetolivertransplantinpretextivhepatoblastoma

Ejemplares similares