Cargando…

Elevated limb-bud and heart development (LBH) expression indicates poor prognosis and promotes gastric cancer cell proliferation and invasion via upregulating Integrin/FAK/Akt pathway

The limb-bud and heart development (LBH) gene is a highly conserved, tissue-specific transcription cofactor in vertebrates that regulates multiple key genes in embryonic development. The role of LBH in various cancer types is still controversial, and its specific role and molecular mechanism in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Ruoxi, Li, Zhi, Zhang, Chuang, Song, Huicong, Deng, Mingming, Sun, Liping, Xu, Ling, Che, Xiaofang, Hu, Xuejun, Qu, Xiujuan, Liu, Yunpeng, Zhang, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2019
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507893/ https://www.ncbi.nlm.nih.gov/pubmed/31119084 http://dx.doi.org/10.7717/peerj.6885

Ejemplares similares

Limb‐bud and heart development (LBH) contributes to glioma progression in vitro and in vivo
por: Liu, Luotong, et al.
Publicado: (2021)

Limb-Bud and Heart (LBH) Upregulation in Cardiomyocytes under Hypoxia Promotes the Activation of Cardiac Fibroblasts via Exosome Secretion
por: Xu, Yuling, et al.
Publicado: (2022)

NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer
por: Yan, Hongfei, et al.
Publicado: (2019)

Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia
por: Jiang, Yang, et al.
Publicado: (2019)

Integrin α5 promotes migration and invasion through the FAK/STAT3/AKT signaling pathway in icotinib-resistant non-small cell lung cancer cells
por: Yang, Yang, et al.
Publicado: (2021)

Limb-bud and Heart (LBH) Functions as a Tumor Suppressor of Nasopharyngeal Carcinoma by Inducing G1/S Cell Cycle Arrest
por: Liu, Qicai, et al.
Publicado: (2015)

LncRNA MIR31HG Drives Oncogenicity by Inhibiting the Limb-Bud and Heart Development Gene (LBH) during Oral Carcinoma
por: Chang, Kuo-Wei, et al.
Publicado: (2021)

Loss of inner kinetochore genes is associated with the transition to an unconventional point centromere in budding yeast
por: Vijay, Nagarjun
Publicado: (2020)

Comprehensive analysis of genes based on chr1p/19q co-deletion reveals a robust 4-gene prognostic signature for lower grade glioma
por: Zhang, Chuang, et al.
Publicado: (2019)

A novel hybrid algorithm based on Harris Hawks for tumor feature gene selection
por: Liu, Junjian, et al.
Publicado: (2023)

Upregulated TUBG1 expression is correlated with poor prognosis in hepatocellular carcinoma
por: Zhang, Kainan, et al.
Publicado: (2022)

MicroRNA-1224 Inhibits Tumor Metastasis in Intestinal-Type Gastric Cancer by Directly Targeting FAK
por: Wang, Jin, et al.
Publicado: (2019)

Diagnostic and prognostic values of upregulated SPC25 in patients with hepatocellular carcinoma
por: Yang, Xiaolin, et al.
Publicado: (2020)

Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway
por: Huang, Chun-Yung, et al.
Publicado: (2009)

Multi-cancer analysis reveals universal association of oncogenic LBH expression with DNA hypomethylation and WNT-Integrin signaling pathways
por: Young, In-Chi, et al.
Publicado: (2023)

Identification and characterization of critical genes associated with tamoxifen resistance in breast cancer
por: Zhang, Kai, et al.
Publicado: (2020)

Molecular analysis of the 14-3-3 genes in Panax ginseng and their responses to heat stress
por: Wang, Qi, et al.
Publicado: (2023)

Upregulated expression of pyruvate kinase M2 mRNA predicts poor prognosis in lung adenocarcinoma
por: Wang, Guiping, et al.
Publicado: (2020)

Upregulation of desmoglein 2 and its clinical value in lung adenocarcinoma: a comprehensive analysis by multiple bioinformatics methods
por: Sun, Ruiying, et al.
Publicado: (2020)

miR-21 is upregulated, promoting fibrosis and blocking G2/M in irradiated rat cardiac fibroblasts
por: Guo, Huan, et al.
Publicado: (2020)

Identification and validation of key genes associated with pathogenesis and prognosis of gastric cancer
por: Li, Ai, et al.
Publicado: (2023)

The effect of walking speed on the foot inter-segment kinematics, ground reaction forces and lower limb joint moments
por: Sun, Dong, et al.
Publicado: (2018)

Hypoxia induced LBH overexpression accelerates malignant progression in glioma
por: Zhang, Ke-Nan, et al.
Publicado: (2019)

Overexpression of LBH is associated with poor prognosis in human hepatocellular carcinoma
por: Chen, Jiewei, et al.
Publicado: (2018)

Identification of key genes associated with multiple sclerosis based on gene expression data from peripheral blood mononuclear cells
por: Shang, Zhenwei, et al.
Publicado: (2020)

Metabolome and transcriptome analyses identify the characteristics and expression of related saponins of the three genealogical plants of bead ginseng
por: Ye, Yihan, et al.
Publicado: (2023)

Survival prediction in patients with colon adenocarcinoma via multiomics data integration using a deep learning algorithm
por: Lv, Jiudi, et al.
Publicado: (2020)

Genome-wide identification of alcohol dehydrogenase (ADH) gene family under waterlogging stress in wheat (Triticum aestivum)
por: Shen, Changwei, et al.
Publicado: (2021)

Cell division cycle associated 2 (CDCA2) upregulation promotes the progression of hepatocellular carcinoma in a p53-dependant manner
por: Wang, Jiahui, et al.
Publicado: (2022)

A novel machine learning derived RNA-binding protein gene–based score system predicts prognosis of hepatocellular carcinoma patients
por: Zhang, Qiangnu, et al.
Publicado: (2021)

Identification of cell division cycle 20 as a candidate biomarker and potential therapeutic target in bladder cancer using bioinformatics analysis
por: Shen, Peilin, et al.
Publicado: (2020)

Mining of prognosis-related genes in cervical squamous cell carcinoma immune microenvironment
por: Ma, Jiong, et al.
Publicado: (2020)

Identification of special key genes for alcohol-related hepatocellular carcinoma through bioinformatic analysis
por: Zhang, Xiuzhi, et al.
Publicado: (2019)

Multiomics-based analyses of KPNA2 highlight its multiple potentials in hepatocellular carcinoma
por: Zhang, Jinzhong, et al.
Publicado: (2021)

Genome-wide analysis suggests high level of microsynteny and purifying selection affect the evolution of EIN3/EIL family in Rosaceae
por: Cao, Yunpeng, et al.
Publicado: (2017)

Identification of exosomal miRNAs associated with the anthracycline-induced liver injury in postoperative breast cancer patients by small RNA sequencing
por: Zhang, Yue, et al.
Publicado: (2020)

Localization of GPSM2 in the Nucleus of Invasive Breast Cancer Cells Indicates a Poor Prognosis
por: Deng, Mingming, et al.
Publicado: (2020)

Integrin and FAK Regulation of Human Pluripotent Stem Cells
por: Vitillo, Loriana, et al.
Publicado: (2017)

Development and validation of ferroptosis-related lncRNAs signature for hepatocellular carcinoma
por: Liang, Jiaying, et al.
Publicado: (2021)

Correlations between glycolysis with clinical traits and immune function in bladder urothelial carcinoma
por: Che, Kai, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nbcf0h5um4odbhk5pvsl1jluot