Changes E3 ubiquitin protein ligase 1 gene mRNA expression correlated with IgA1 glycosylation in patients with IgA nephropathy

Background: Recent genomewide association study suggested that the top single-nucleotide polymorphism, rs978056, in HECW1 gene (which encodes HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1) associated with the levels of galactose-deficient IgA1 (Gd-IgA1) in IgA nephropathy (IgAN). H...

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Detalles Bibliográficos
Autores principales: Liu, Youxia, Zheng, Jie, Jia, Junya, Li, Hongfen, Hu, Shuiyi, Lin, Yujia, Yan, Tiekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508078/
https://www.ncbi.nlm.nih.gov/pubmed/31057023
http://dx.doi.org/10.1080/0886022X.2019.1605295

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