Derivation of mimetic γδ T cells endowed with cancer recognition receptors from reprogrammed γδ T cell

Using induced pluripotent stem cells (iPSCs) to derive chimeric antigen receptor-modified T (CAR-T) cells has great industrial potential. A previous study used αβ T cell-derived CAR-modified iPSCs to produce CAR-T cells. However, these αβ T cells are restricted to autologous use and only recognize s...

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Detalles Bibliográficos
Autores principales: Zeng, Jieming, Tang, Shin Yi, Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508724/
https://www.ncbi.nlm.nih.gov/pubmed/31071196
http://dx.doi.org/10.1371/journal.pone.0216815

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