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Molluscum contagiosum virus MC80 sabotages MHC-I antigen presentation by targeting tapasin for ER-associated degradation

The human specific poxvirus molluscum contagiosum virus (MCV) produces skin lesions that can persist with minimal inflammation, suggesting that the virus has developed robust immune evasion strategies. However, investigations into the underlying mechanisms of MCV pathogenesis have been hindered by t...

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Detalles Bibliográficos
Autores principales: Harvey, Ian B., Wang, Xiaoli, Fremont, Daved H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508746/
https://www.ncbi.nlm.nih.gov/pubmed/31034515
http://dx.doi.org/10.1371/journal.ppat.1007711

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