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Finding driver mutations in cancer: Elucidating the role of background mutational processes
Identifying driver mutations in cancer is notoriously difficult. To date, recurrence of a mutation in patients remains one of the most reliable markers of mutation driver status. However, some mutations are more likely to occur than others due to differences in background mutation rates arising from...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508748/ https://www.ncbi.nlm.nih.gov/pubmed/31034466 http://dx.doi.org/10.1371/journal.pcbi.1006981 |