Cargando…

Complement Component C3 Binds to the A3 Domain of von Willebrand Factor

von Willebrand factor (VWF) is a multimeric protein composed of monomeric subunits (∼280 kD) linked by disulfide bonds. During hemostasis and thrombosis, ultralarge (UL) VWF (ULVWF) multimers initiate platelet adhesion. In vitro, human C3 binds to ULVWF multimeric strings secreted by and anchored to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nolasco, Jennifer G., Nolasco, Leticia H., Da, Qi, Cirlos, Sonya, Ruggeri, Zaverio M., Moake, Joel L., Cruz, Miguel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Georg Thieme Verlag KG 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508891/ https://www.ncbi.nlm.nih.gov/pubmed/31080944 http://dx.doi.org/10.1055/s-0038-1672189

Ejemplares similares

Assembly and Activation of Alternative Complement Components on Endothelial Cell-Anchored Ultra-Large Von Willebrand Factor Links Complement and Hemostasis-Thrombosis
por: Turner, Nancy A., et al.
Publicado: (2013)

The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse
por: Kanaji, Sachiko, et al.
Publicado: (2022)

Space and Time Resolved Detection of Platelet Activation and von Willebrand Factor Conformational Changes in Deep Suspensions
por: Biasetti, Jacopo, et al.
Publicado: (2017)

Proteolysis of Von Willebrand Factor Influences Inflammatory Endothelial Activation and Vascular Compliance in Atherosclerosis
por: Ozawa, Koya, et al.
Publicado: (2020)

Heat-inactivated Factor B inhibits alternative pathway fluid-phase activation and convertase formation on endothelial cell-secreted ultra-large von Willebrand factor strings
por: Turner, Nancy A., et al.
Publicado: (2023)

Recombinant von Willebrand factor prophylaxis in patients with severe von Willebrand disease: phase 3 study results
por: Leebeek, Frank W. G., et al.
Publicado: (2022)

Fibronectin binding to von Willebrand factor occurs via the A1 domain
por: Keesler, Daniel A., et al.
Publicado: (2021)

The Functions of the A1A2A3 Domains in Von Willebrand Factor Include Multimerin 1 Binding
por: Parker, D’Andra N., et al.
Publicado: (2016)

Hemophilia and von Willebrand disease: Factor VIII and von Willebrand factor
por: Sharma, Prashant
Publicado: (2019)

von Willebrand Factor, Free Hemoglobin and Thrombosis in ECMO
por: Valladolid, Christian, et al.
Publicado: (2018)

Pharmacokinetic-Pharmacodynamic Comparison of Recombinant and Plasma-Derived von Willebrand Factor in Patients with von Willebrand Disease Type 3
por: Bauer, Alexander, et al.
Publicado: (2023)

Diagnostic Value of Measuring Platelet Von Willebrand Factor in Von Willebrand Disease
por: Casonato, Alessandra, et al.
Publicado: (2016)

The von Willebrand factor A-1 domain binding aptamer BT200 elevates plasma levels of von Willebrand factor and factor VIII: a first-in-human trial
por: Kovacevic, Katarina D., et al.
Publicado: (2021)

A conformational transition of the D′D3 domain primes von Willebrand factor for multimerization
por: Gruber, Sophia, et al.
Publicado: (2022)

Phase 3 study of recombinant von Willebrand factor in patients with severe von Willebrand disease who are undergoing elective surgery
por: Peyvandi, F., et al.
Publicado: (2018)

Von Willebrand factor propeptide and pathophysiological mechanisms in European and Iranian patients with type 3 von Willebrand disease enrolled in the 3WINTERS‐IPS study
por: Pagliari, Maria Teresa, et al.
Publicado: (2022)

Changes of von Willebrand Factor during Pregnancy in Women with and without von Willebrand Disease
por: Castaman, Giancarlo
Publicado: (2013)

Genetic Variation in the von Willebrand Factor Gene in Swedish von Willebrand Disease Patients
por: Manderstedt, Eric, et al.
Publicado: (2018)

Substitutions at position 263 within the von Willebrand factor type A domain determine the functionality of complement C2 protein
por: Kuźniewska, Alicja, et al.
Publicado: (2022)

Interaction Between the a3 Region of Factor VIII and the TIL’E’ Domains of the von Willebrand Factor
por: Dagil, Lisbeth, et al.
Publicado: (2019)

Von Willebrand Disease: An Overview
por: Bharati, K. Pavani, et al.
Publicado: (2011)

On the Versatility of von Willebrand Factor
por: Rauch, Antoine, et al.
Publicado: (2013)

Of von Willebrand factor and platelets
por: Bryckaert, Marijke, et al.
Publicado: (2014)

Differential surface activation of the A1 domain of von Willebrand factor
por: Tronic, Elaine H., et al.
Publicado: (2016)

The Interaction between Factor H and Von Willebrand Factor
por: Feng, Shuju, et al.
Publicado: (2013)

Porcine and Canine von Willebrand Factor and von Willebrand Disease: Hemostasis, Thrombosis, and Atherosclerosis Studies
por: Nichols, Timothy C., et al.
Publicado: (2010)

Classification of von Willebrand disease in the context of modern contemporary von Willebrand factor testing methodologies
por: Favaloro, Emmanuel J.
Publicado: (2020)

Improving diagnosis of von Willebrand disease: Reference ranges for von Willebrand factor multimer distribution
por: Vangenechten, Inge, et al.
Publicado: (2020)

Differences in von Willebrand factor function in type 2A von Willebrand disease and left ventricular assist device‐induced acquired von Willebrand syndrome
por: Deconinck, Shannen, et al.
Publicado: (2018)

Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domain
por: Campbell, James C., et al.
Publicado: (2016)

Evaluation of von Willebrand factor in COPD patients
por: Bártholo, Thiago Prudente, et al.
Publicado: (2014)

D’ domain region Arg782-Cys799 of von Willebrand factor contributes to factor VIII binding
por: Przeradzka, Małgorzata A., et al.
Publicado: (2020)

von Willebrand factor levels in the diagnosis of von Willebrand disease: a systematic review and meta-analysis
por: Kalot, Mohamad A., et al.
Publicado: (2021)

Binding of von Willebrand Factor to Complement C1q Decreases the Phagocytosis of Cholesterol Crystals and Subsequent IL-1 Secretion in Macrophages
por: Donat, Claudia, et al.
Publicado: (2019)

Quantitative 3D microscopy highlights altered von Willebrand factor α‐granule storage in patients with von Willebrand disease with distinct pathogenic mechanisms
por: Swinkels, Maurice, et al.
Publicado: (2021)

Calcium modulates force sensing by the von Willebrand factor A2 domain
por: Jakobi, Arjen J., et al.
Publicado: (2011)

Treatment of patients with von Willebrand disease
por: Tuohy, Emma, et al.
Publicado: (2011)

The Molecular Genetics of von Willebrand Disease
por: Berber, Ergül
Publicado: (2012)

Von Willebrand Factor, Angiodysplasia and Angiogenesis
por: Randi, Anna M., et al.
Publicado: (2013)

Regulation of plasma von Willebrand factor
por: Desch, Karl C
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0mvro80dide9l13fmn22iauc67