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The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway

Objective: The senescence of nucleus pulposus (NP) cells induced by oxidative stress is one of the important causes of intervertebral disc degeneration (IDD). Herein, we investigated the role and action mechanism of silent information regulator 1 (SIRT1) in oxidative stress-induced senescence of rat...

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Detalles Bibliográficos
Autores principales:	He, Junsheng, Zhang, Ailiang, Song, Zhiwen, Guo, Shiwu, Chen, Yuwei, Liu, Zhiyuan, Zhang, Jinlong, Xu, Xu, Liu, Jinbo, Chu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509061/ https://www.ncbi.nlm.nih.gov/pubmed/30967498 http://dx.doi.org/10.1042/BSR20190112

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