CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality

Pulmonary immune control is crucial for protection against pathogens. Here we identify a pathway that promotes host responses during pulmonary bacterial infection; the expression of CD200 receptor (CD200R), which is known to dampen pulmonary immune responses, promotes effective clearance of the leth...

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Detalles Bibliográficos
Autores principales: Casulli, J., Fife, M. E., Houston, S. A., Rossi, S., Dow, J., Williamson, E. D., Clark, G. C, Hussell, T., D’Elia, R. V., Travis, M. A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509168/
https://www.ncbi.nlm.nih.gov/pubmed/31073183
http://dx.doi.org/10.1038/s41467-019-10156-6

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