Regulation of Wnt Singaling Pathway by Poly (ADP-Ribose) Glycohydrolase (PARG) Silencing Suppresses Lung Cancer in Mice Induced by Benzo(a)pyrene Inhalation Exposure

Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon that specifically causes cancer and is widely distributed in the environment. Poly (ADP-ribosylation), as a key post-translational modification in BaP-induced carcinogenesis, is mainly catalyzed by poly (ADP-ribose) glycohydrolase (PARG) in e...

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Detalles Bibliográficos
Autores principales: Dai, Wenjuan, Fu, Yingbin, Deng, Yanxia, Zeng, Zhuoying, Gu, Pan, Liu, Hailong, Liu, Jianjun, Xu, Xinyun, Wu, Desheng, Luo, Xianru, Yang, Linqing, Zhang, Jinzhou, Lin, Kai, Hu, Gonghua, Huang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509174/
https://www.ncbi.nlm.nih.gov/pubmed/31130856
http://dx.doi.org/10.3389/fphar.2019.00338

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