Cargando…

YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma

YTH N6-methyladenosine (m6A) RNA binding protein 1 (YTHDF1) is a core factor in RNA methylation modification. Recent studies have shown that m6A is closely related to multiple tumors, thus YTHDF1 may also play a role in tumorigenesis. This study, aimed to explore the role of YTHDF1 in the colorectal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bai, Yang, Yang, Chunxing, Wu, Runliu, Huang, Lihua, Song, Shenlei, Li, Wanwan, Yan, Peichen, Lin, Changwei, Li, Daojiang, Zhang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509179/ https://www.ncbi.nlm.nih.gov/pubmed/31131257 http://dx.doi.org/10.3389/fonc.2019.00332

Ejemplares similares

DEAD-box helicase 27 plays a tumor-promoter role by regulating the stem cell-like activity of human colorectal cancer cells
por: Yang, Chunxing, et al.
Publicado: (2018)

Study of Promoter Methylation Patterns of HOXA2, HOXA5, and HOXA6 and Its Clinicopathological Characteristics in Colorectal Cancer
por: Li, Daojiang, et al.
Publicado: (2019)

PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness
por: Li, Daojiang, et al.
Publicado: (2019)

POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling
por: Du, Yuheng, et al.
Publicado: (2018)

Overexpression of NELFCD promotes colorectal cancer cells proliferation, migration, and invasion
por: Song, Shenglei, et al.
Publicado: (2018)

Comprehensive bioinformatics analysis of the characterization and determination underlying mechanisms of over-expression and co-expression of genes residing on 20q in colorectal cancer
por: Li, Daojiang, et al.
Publicado: (2017)

Berberine Suppresses Stemness and Tumorigenicity of Colorectal Cancer Stem-Like Cells by Inhibiting m(6)A Methylation
por: Zhao, Ziyi, et al.
Publicado: (2021)

Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3′-untranslated region in colorectal cancer
por: Su, Chen, et al.
Publicado: (2018)

Prognostic and predictive value of YTHDF1 and YTHDF2 and their correlation with tumor-infiltrating immune cells in non-small cell carcinoma
por: Koh, Young Wha, et al.
Publicado: (2022)

Prognostic Value of YTHDF2 in Clear Cell Renal Cell Carcinoma
por: Mu, Zhongyi, et al.
Publicado: (2020)

Overexpressed PLAGL2 transcriptionally activates Wnt6 and promotes cancer development in colorectal cancer
por: Li, Nanpeng, et al.
Publicado: (2019)

GALC Triggers Tumorigenicity of Colorectal Cancer via Senescent Fibroblasts
por: Yang, Mengdi, et al.
Publicado: (2020)

Cholesterol in colorectal cancer: an essential but tumorigenic precursor?
por: He, Xing, et al.
Publicado: (2023)

YTHDF1 Is a Potential Pan-Cancer Biomarker for Prognosis and Immunotherapy
por: Hu, Jian, et al.
Publicado: (2021)

Scutellaria barbata Inhibits Hepatocellular Carcinoma Tumorigenicity by Inducing Ferroptosis of Hepatocellular Carcinoma Cells
por: Li, Yue, et al.
Publicado: (2022)

The Role of HER2 in Self-Renewal, Invasion, and Tumorigenicity of Gastric Cancer Stem Cells
por: Sun, Li-Fei, et al.
Publicado: (2020)

Potential Impact of ALKBH5 and YTHDF1 on Tumor Immunity in Colon Adenocarcinoma
por: Yan, Guanyu, et al.
Publicado: (2021)

Comprehensive analysis of differentially expressed profiles of lncRNAs and construction of miR-133b mediated ceRNA network in colorectal cancer
por: Wu, Hao, et al.
Publicado: (2017)

The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression
por: Wu, Runliu, et al.
Publicado: (2020)

YTHDF1 Aggravates the Progression of Cervical Cancer Through m(6)A-Mediated Up-Regulation of RANBP2
por: Wang, Haocheng, et al.
Publicado: (2021)

Pro-tumorigenic role of type 2 diabetes-induced cellular senescence in colorectal cancer
por: Melia, Francesco, et al.
Publicado: (2022)

To Become or Not to Become Tumorigenic: Subventricular Zone Versus Hippocampal Neural Stem Cells
por: Fontán-Lozano, Ángela, et al.
Publicado: (2020)

Downregulation of ZNF280A inhibits proliferation and tumorigenicity of colorectal cancer cells by promoting the ubiquitination and degradation of RPS14
por: Tian, Binle, et al.
Publicado: (2022)

The top 100 most cited papers on endometrial carcinoma: A bibliometric analysis
por: Xiao, Peichen, et al.
Publicado: (2022)

Neural stemness contributes to cell tumorigenicity
por: Xu, Liyang, et al.
Publicado: (2021)

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma
por: Chen, Jia-Jie, et al.
Publicado: (2015)

ALKBH5 regulates STAT3 activity to affect the proliferation and tumorigenicity of osteosarcoma via an m6A-YTHDF2-dependent manner
por: Yang, Zechuan, et al.
Publicado: (2022)

YTHDF2 inhibit the tumorigenicity of endometrial cancer via downregulating the expression of IRS1 methylated with m(6)A
por: Hong, Ling, et al.
Publicado: (2021)

Transcriptome Based System Biology Exploration Reveals Homogeneous Tumorigenicity of Alimentary Tract Malignancy
por: Lu, Yu-Chen, et al.
Publicado: (2021)

Long Noncoding RNA AFAP1-AS1 Is a Critical Regulator of Nasopharyngeal Carcinoma Tumorigenicity
por: Fang, Min, et al.
Publicado: (2020)

ECT2 Increases the stability of EGFR and Tumorigenicity by Inhibiting Grb2 Ubiquitination in Pancreatic Cancer
por: Wang, Junxiong, et al.
Publicado: (2021)

YTHDF3 as a new player in hematopoietic stem cell regulation
por: Mao, Xinjian, et al.
Publicado: (2022)

Pro-Tumorigenic Macrophage Infiltration in Oral Squamous Cell Carcinoma and Possible Macrophage-Aimed Therapeutic Interventions
por: Bruna, Flavia, et al.
Publicado: (2021)

Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential
por: Zhang, Min, et al.
Publicado: (2022)

Tumorigenic bacteria in colorectal cancer: mechanisms and treatments
por: Li, Sha, et al.
Publicado: (2022)

Highly tumorigenic hepatocellular carcinoma cell line with cancer stem cell-like properties
por: Lacoste, Benoit, et al.
Publicado: (2017)

YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation
por: Li, Jiong, et al.
Publicado: (2021)

A Pro-Tumorigenic Effect of Heparanase 2 (Hpa2) in Thyroid Carcinoma Involves Its Localization to the Nuclear Membrane
por: Margulis, Itai, et al.
Publicado: (2021)

GMEB2 Promotes the Growth of Colorectal Cancer by Activating ADRM1 Transcription and NF-κB Signalling and Is Positively Regulated by the m(6)A Reader YTHDF1
por: Ning, Zhengping, et al.
Publicado: (2022)

YTHDF2 Inhibits the Migration and Invasion of Lung Adenocarcinoma by Negatively Regulating the FAM83D-TGFβ1-SMAD2/3 Pathway
por: Zhao, Teng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7d0vds4grvi566j1dq79t1v223