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Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway

Viral infections induce proinflammatory signaling cascades and inflammatory cytokine production, which is precisely regulated for host benefits. In the current study, we unravel a previously unappreciated role of nonmuscle myosin heavy chain IIA (NMHC-IIA) as a negative regulator in inflammatory res...

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Detalles Bibliográficos
Autores principales: Liu, Yingqi, Li, Rui, Chen, Xin-xin, Zhi, Yubao, Deng, Ruiguang, Zhou, En-min, Qiao, Songlin, Zhang, Gaiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509187/
https://www.ncbi.nlm.nih.gov/pubmed/31064828
http://dx.doi.org/10.1128/mBio.00574-19