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Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation

BACKGROUND: Positron emission tomography (PET) can be used for in vivo evaluation of the pathology associated with multiple sclerosis. We investigated the use of longitudinal PET imaging and the 18-kDa translocator protein (TSPO) binding radioligand [(18)F]GE-180 to detect changes in a chronic multi...

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Detalles Bibliográficos
Autores principales:	Vainio, S. K., Dickens, A. M., Tuisku, J., Eskola, O., Solin, O., Löyttyniemi, E., Anthony, D. C., Rinne, J. O., Airas, L., Haaparanta-Solin, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509289/ https://www.ncbi.nlm.nih.gov/pubmed/31073768 http://dx.doi.org/10.1186/s13550-019-0508-7

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