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Lipoprotein(a) Particle Production as a Determinant of Plasma Lipoprotein(a) Concentration Across Varying Apolipoprotein(a) Isoform Sizes and Background Cholesterol‐Lowering Therapy

BACKGROUND: Elevated lipoprotein(a) (Lp(a)), a low‐density lipoprotein‐like particle bound to the polymorphic apolipoprotein(a) (apo(a)), may be causal for cardiovascular disease. However, the metabolism of Lp(a) in humans is poorly understood. METHODS AND RESULTS: We investigated the kinetics of Lp...

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Detalles Bibliográficos
Autores principales:	Chan, Dick C., Watts, Gerald F., Coll, Blai, Wasserman, Scott M., Marcovina, Santica M., Barrett, P. Hugh R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509712/ https://www.ncbi.nlm.nih.gov/pubmed/30897995 http://dx.doi.org/10.1161/JAHA.118.011781

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