Efficacy and Safety of Bempedoic Acid in Patients With Hypercholesterolemia and Statin Intolerance

BACKGROUND: Inability to tolerate statins because of muscle symptoms contributes to uncontrolled cholesterol levels and insufficient cardiovascular risk reduction. Bempedoic acid, a prodrug that is activated by a hepatic enzyme not present in skeletal muscle, inhibits ATP‐citrate lyase, an enzyme up...

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Detalles Bibliográficos
Autores principales: Laufs, Ulrich, Banach, Maciej, Mancini, G. B. John, Gaudet, Daniel, Bloedon, LeAnne T., Sterling, Lulu Ren, Kelly, Stephanie, Stroes, Erik S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509724/
https://www.ncbi.nlm.nih.gov/pubmed/30922146
http://dx.doi.org/10.1161/JAHA.118.011662

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