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Low expression of ACLY associates with favorable prognosis in acute myeloid leukemia

BACKGROUND: Aberrant metabolism is a hallmark of cancer cells. Recently, ATP citrate-lyase (ACLY) expression was demonstrated as an independent predictor of clinical outcome in solid tumors. However, no systematic study was conducted to explore the prognostic impact of ACLY on acute myeloid leukemia...

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Detalles Bibliográficos
Autores principales: Wang, Jinghan, Ye, Wenle, Yan, Xiao, Guo, Qi, Ma, Qiuling, Lin, Fang, Huang, Jiansong, Jin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509777/
https://www.ncbi.nlm.nih.gov/pubmed/31077215
http://dx.doi.org/10.1186/s12967-019-1884-5

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