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The cis-trans binding strength defined by motif frequencies facilitates statistical inference of transcriptional regulation
BACKGROUND: A key problem in systems biology is the determination of the regulatory mechanism corresponding to a phenotype. An empirical approach in this regard is to compare the expression profiles of cells under two conditions or tissues from two phenotypes and to unravel the underlying transcript...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509875/ https://www.ncbi.nlm.nih.gov/pubmed/31074378 http://dx.doi.org/10.1186/s12859-019-2732-6 |