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Combined Effect of Fatty Diet and Cognitive Decline on Brain Metabolism, Food Intake, Body Weight, and Counteraction by Intranasal Insulin Therapy in 3×Tg Mice
Obesity and cognitive decline can occur in association. Brain dysmetabolism and insulin resistance might be common underlying traits. We aimed to examine the effect of high-fat diet (HFD) on cognitive decline, and of cognitive impairment on food intake and body-weight, and explore efficacy of chroni...
Autores principales: | Sanguinetti, Elena, Guzzardi, Maria Angela, Panetta, Daniele, Tripodi, Maria, De Sena, Vincenzo, Quaglierini, Mauro, Burchielli, Silvia, Salvadori, Piero A., Iozzo, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509878/ https://www.ncbi.nlm.nih.gov/pubmed/31130848 http://dx.doi.org/10.3389/fncel.2019.00188 |
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