A case report and focused literature review of d‐penicillamine and severe neutropenia: A serious toxicity from a seldom‐used drug

Prescribing d‐penicillamine for Wilson's disease must be accompanied by vigilant monitoring, including a complete blood cell count with differential. For most, this should occur once or twice weekly during the first month of therapy and during periods of dose escalation, then every two weeks fo...

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Detalles Bibliográficos
Autores principales: Pitman, Stuart K., Huynh, Tony, Bjarnason, Thorarinn A., An, Josiah, Malkhasyan, Karen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509885/
https://www.ncbi.nlm.nih.gov/pubmed/31110732
http://dx.doi.org/10.1002/ccr3.2125
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author Pitman, Stuart K.
Huynh, Tony
Bjarnason, Thorarinn A.
An, Josiah
Malkhasyan, Karen A.
author_facet Pitman, Stuart K.
Huynh, Tony
Bjarnason, Thorarinn A.
An, Josiah
Malkhasyan, Karen A.
author_sort Pitman, Stuart K.
collection PubMed
description Prescribing d‐penicillamine for Wilson's disease must be accompanied by vigilant monitoring, including a complete blood cell count with differential. For most, this should occur once or twice weekly during the first month of therapy and during periods of dose escalation, then every two weeks for six additional months, then monthly.
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spelling pubmed-65098852019-05-20 A case report and focused literature review of d‐penicillamine and severe neutropenia: A serious toxicity from a seldom‐used drug Pitman, Stuart K. Huynh, Tony Bjarnason, Thorarinn A. An, Josiah Malkhasyan, Karen A. Clin Case Rep Case Reports Prescribing d‐penicillamine for Wilson's disease must be accompanied by vigilant monitoring, including a complete blood cell count with differential. For most, this should occur once or twice weekly during the first month of therapy and during periods of dose escalation, then every two weeks for six additional months, then monthly. John Wiley and Sons Inc. 2019-04-09 /pmc/articles/PMC6509885/ /pubmed/31110732 http://dx.doi.org/10.1002/ccr3.2125 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Pitman, Stuart K.
Huynh, Tony
Bjarnason, Thorarinn A.
An, Josiah
Malkhasyan, Karen A.
A case report and focused literature review of d‐penicillamine and severe neutropenia: A serious toxicity from a seldom‐used drug
title A case report and focused literature review of d‐penicillamine and severe neutropenia: A serious toxicity from a seldom‐used drug
title_full A case report and focused literature review of d‐penicillamine and severe neutropenia: A serious toxicity from a seldom‐used drug
title_fullStr A case report and focused literature review of d‐penicillamine and severe neutropenia: A serious toxicity from a seldom‐used drug
title_full_unstemmed A case report and focused literature review of d‐penicillamine and severe neutropenia: A serious toxicity from a seldom‐used drug
title_short A case report and focused literature review of d‐penicillamine and severe neutropenia: A serious toxicity from a seldom‐used drug
title_sort case report and focused literature review of d‐penicillamine and severe neutropenia: a serious toxicity from a seldom‐used drug
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509885/
https://www.ncbi.nlm.nih.gov/pubmed/31110732
http://dx.doi.org/10.1002/ccr3.2125
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