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Eccentric Muscle Contractions: Risks and Benefits
Eccentric contractions, characterized by the lengthening of the muscle-tendon complex, present several unique features compared with other types of contractions, which may lead to unique adaptations. Due to its specific physiological and mechanical properties, there is an increasing interest in empl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510035/ https://www.ncbi.nlm.nih.gov/pubmed/31130877 http://dx.doi.org/10.3389/fphys.2019.00536 |
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author | Hody, Stéphanie Croisier, Jean-Louis Bury, Thierry Rogister, Bernard Leprince, Pierre |
author_facet | Hody, Stéphanie Croisier, Jean-Louis Bury, Thierry Rogister, Bernard Leprince, Pierre |
author_sort | Hody, Stéphanie |
collection | PubMed |
description | Eccentric contractions, characterized by the lengthening of the muscle-tendon complex, present several unique features compared with other types of contractions, which may lead to unique adaptations. Due to its specific physiological and mechanical properties, there is an increasing interest in employing eccentric muscle work for rehabilitation and clinical purposes. However, unaccustomed eccentric exercise is known to cause muscle damage and delayed pain, commonly defined as “Delayed-Onset Muscular Soreness” (DOMS). To date, the most useful preventive strategy to avoid these adverse effects consists of repeating sessions involving submaximal eccentric contractions whose intensity is progressively increased over the training. Despite an increased number of investigations focusing on the eccentric contraction, a significant gap still remains in our understanding of the cellular and molecular mechanisms underlying the initial damage response and subsequent adaptations to eccentric exercise. Yet, unraveling the molecular basis of exercise-related muscle damage and soreness might help uncover the mechanistic basis of pathological conditions as myalgia or neuromuscular diseases. In addition, a better insight into the mechanisms governing eccentric training adaptations should provide invaluable information for designing therapeutic interventions and identifying potential therapeutic targets. |
format | Online Article Text |
id | pubmed-6510035 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-65100352019-05-24 Eccentric Muscle Contractions: Risks and Benefits Hody, Stéphanie Croisier, Jean-Louis Bury, Thierry Rogister, Bernard Leprince, Pierre Front Physiol Physiology Eccentric contractions, characterized by the lengthening of the muscle-tendon complex, present several unique features compared with other types of contractions, which may lead to unique adaptations. Due to its specific physiological and mechanical properties, there is an increasing interest in employing eccentric muscle work for rehabilitation and clinical purposes. However, unaccustomed eccentric exercise is known to cause muscle damage and delayed pain, commonly defined as “Delayed-Onset Muscular Soreness” (DOMS). To date, the most useful preventive strategy to avoid these adverse effects consists of repeating sessions involving submaximal eccentric contractions whose intensity is progressively increased over the training. Despite an increased number of investigations focusing on the eccentric contraction, a significant gap still remains in our understanding of the cellular and molecular mechanisms underlying the initial damage response and subsequent adaptations to eccentric exercise. Yet, unraveling the molecular basis of exercise-related muscle damage and soreness might help uncover the mechanistic basis of pathological conditions as myalgia or neuromuscular diseases. In addition, a better insight into the mechanisms governing eccentric training adaptations should provide invaluable information for designing therapeutic interventions and identifying potential therapeutic targets. Frontiers Media S.A. 2019-05-03 /pmc/articles/PMC6510035/ /pubmed/31130877 http://dx.doi.org/10.3389/fphys.2019.00536 Text en Copyright © 2019 Hody, Croisier, Bury, Rogister and Leprince. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Hody, Stéphanie Croisier, Jean-Louis Bury, Thierry Rogister, Bernard Leprince, Pierre Eccentric Muscle Contractions: Risks and Benefits |
title | Eccentric Muscle Contractions: Risks and Benefits |
title_full | Eccentric Muscle Contractions: Risks and Benefits |
title_fullStr | Eccentric Muscle Contractions: Risks and Benefits |
title_full_unstemmed | Eccentric Muscle Contractions: Risks and Benefits |
title_short | Eccentric Muscle Contractions: Risks and Benefits |
title_sort | eccentric muscle contractions: risks and benefits |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510035/ https://www.ncbi.nlm.nih.gov/pubmed/31130877 http://dx.doi.org/10.3389/fphys.2019.00536 |
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