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Proton pump inhibitors induce hemolytic anemia
Proton pump inhibitors (PPIs) are generally safe, and their short-term use commonly does not induce hemolytic anemia. The underlying mechanisms are unknown, and the literature insufficiently explores hemolytic anemia as an adverse event induced by PPIs. In this case study, we report a 31-year-old fe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510101/ https://www.ncbi.nlm.nih.gov/pubmed/31143745 http://dx.doi.org/10.4103/jfmpc.jfmpc_169_19 |
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author | Al-Nasser, Asayil Nasser Husain, Raja Saleh Al-Marhabi, Ahmed Abdullah |
author_facet | Al-Nasser, Asayil Nasser Husain, Raja Saleh Al-Marhabi, Ahmed Abdullah |
author_sort | Al-Nasser, Asayil Nasser |
collection | PubMed |
description | Proton pump inhibitors (PPIs) are generally safe, and their short-term use commonly does not induce hemolytic anemia. The underlying mechanisms are unknown, and the literature insufficiently explores hemolytic anemia as an adverse event induced by PPIs. In this case study, we report a 31-year-old female who had developed hemolytic anemia with symptoms of jaundice, hyperbilirubinemia, and high reticulocytes, after treatment with PPI. Interestingly, the patient completely recovered after PPI withdrawal. This present case study highlights the need for physicians to exercise caution when treating patients with PPI. |
format | Online Article Text |
id | pubmed-6510101 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-65101012019-05-29 Proton pump inhibitors induce hemolytic anemia Al-Nasser, Asayil Nasser Husain, Raja Saleh Al-Marhabi, Ahmed Abdullah J Family Med Prim Care Case Report Proton pump inhibitors (PPIs) are generally safe, and their short-term use commonly does not induce hemolytic anemia. The underlying mechanisms are unknown, and the literature insufficiently explores hemolytic anemia as an adverse event induced by PPIs. In this case study, we report a 31-year-old female who had developed hemolytic anemia with symptoms of jaundice, hyperbilirubinemia, and high reticulocytes, after treatment with PPI. Interestingly, the patient completely recovered after PPI withdrawal. This present case study highlights the need for physicians to exercise caution when treating patients with PPI. Medknow Publications & Media Pvt Ltd 2019-04 /pmc/articles/PMC6510101/ /pubmed/31143745 http://dx.doi.org/10.4103/jfmpc.jfmpc_169_19 Text en Copyright: © 2019 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Al-Nasser, Asayil Nasser Husain, Raja Saleh Al-Marhabi, Ahmed Abdullah Proton pump inhibitors induce hemolytic anemia |
title | Proton pump inhibitors induce hemolytic anemia |
title_full | Proton pump inhibitors induce hemolytic anemia |
title_fullStr | Proton pump inhibitors induce hemolytic anemia |
title_full_unstemmed | Proton pump inhibitors induce hemolytic anemia |
title_short | Proton pump inhibitors induce hemolytic anemia |
title_sort | proton pump inhibitors induce hemolytic anemia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510101/ https://www.ncbi.nlm.nih.gov/pubmed/31143745 http://dx.doi.org/10.4103/jfmpc.jfmpc_169_19 |
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