Cargando…

Long noncoding RNA DLX6-AS1 promotes tumorigenesis by modulating miR-497-5p/FZD4/FZD6/Wnt/β-catenin pathway in pancreatic cancer

BACKGROUND: Long noncoding RNAs (lncRNAs) are abnormally expressed in various human tumors and play an important role in multiple tumorigeneses, including pancreatic cancer (PC). MATERIALS AND METHODS: The present study was designed to evaluate the role of lncRNA DLX6-AS1 in tumorigenesis of PC. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Jiyong, Ye, Zhen, Mei, Dan, Gu, Honggang, Zhang, Jingzhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510228/ https://www.ncbi.nlm.nih.gov/pubmed/31118816 http://dx.doi.org/10.2147/CMAR.S194453

Ejemplares similares

LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation
por: Chen, Zhenzhen, et al.
Publicado: (2018)

Correction: LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation
por: Chen, Zhenzhen, et al.
Publicado: (2022)

The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets
por: Zacarías-Fluck, Mariano F, et al.
Publicado: (2021)

Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage
por: Corda, G, et al.
Publicado: (2017)

NPTX2 promotes colorectal cancer growth and liver metastasis by the activation of the canonical Wnt/β-catenin pathway via FZD6
por: Xu, Chunjie, et al.
Publicado: (2019)

SOX8 promotes tumor growth and metastasis through FZD6-dependent Wnt/β-catenin signaling in colorectal carcinoma
por: Li, Chen, et al.
Publicado: (2023)

Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer
por: Zhang, Zhongbo, et al.
Publicado: (2021)

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways
por: Zhu, Xuming, et al.
Publicado: (2023)

miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt–β-catenin pathway
por: Liu, Qiang, et al.
Publicado: (2019)

The Expression of Selected Wnt Pathway Members (FZD6, AXIN2 and β-Catenin) in Canine Oral Squamous Cell Carcinoma and Acanthomatous Ameloblastoma
por: Putnová, Barbora, et al.
Publicado: (2021)

FZD6 is a novel gene for human neural tube defects
por: De Marco, Patrizia, et al.
Publicado: (2011)

Sorting nexin 27 interacts with Fzd7 and mediates Wnt signalling
por: Sun, Lixiang, et al.
Publicado: (2016)

Prognostic role of Wnt and Fzd gene families in acute myeloid leukaemia
por: Dai, Yifeng, et al.
Publicado: (2021)

Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer
por: Corda, Gabriele, et al.
Publicado: (2016)

Overexpressed lncRNA GATA6-AS1 Inhibits LNM and EMT via FZD4 through the Wnt/β-Catenin Signaling Pathway in GC
por: Li, Zheng-Tian, et al.
Publicado: (2019)

Prediction of Structure of Human WNT-CRD (FZD) Complex for Computational Drug Repurposing
por: Ain, Qurrat U., et al.
Publicado: (2013)

The FZD7‐TWIST1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma
por: Tan, Ming, et al.
Publicado: (2019)

Decrease of FZD4 exon 1 methylation in probands from FZD4-associated FEVR family of phenotypic heterogeneity
por: Liu, Miaomiao, et al.
Publicado: (2022)

Luteolin attenuates Wnt signaling via upregulation of FZD6 to suppress prostate cancer stemness revealed by comparative proteomics
por: Han, Kun, et al.
Publicado: (2018)

FZD6 expression is negatively regulated by miR-199a-5p in human colorectal cancer
por: Kim, Bong-Kyu, et al.
Publicado: (2015)

FZD7: A potential biomarker for endometriosis
por: Lan, Suwei, et al.
Publicado: (2023)

Regulation of ABCG2 expression by Wnt5a through FZD7 in human pancreatic cancer cells
por: Zhang, Zhongbo, et al.
Publicado: (2021)

Role of WNT5A receptors FZD5 and RYK in prostate cancer cells
por: Thiele, Stefanie, et al.
Publicado: (2018)

Long non-coding RNA CASC9 promotes tumor growth and metastasis via modulating FZD6/Wnt/β-catenin signaling pathway in bladder cancer
por: Zhan, Yonghao, et al.
Publicado: (2020)

Retraction Notice to: Overexpressed lncRNA GATA6-AS1 Inhibits LNM and EMT via FZD4 through the Wnt/β-Catenin Signaling Pathway in GC
por: Li, Zheng-Tian, et al.
Publicado: (2022)

A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways
por: Huang, Tianzhi, et al.
Publicado: (2016)

FZD6 triggers Wnt–signalling driven by WNT10B(IVS1) expression and highlights new targets in T‐cell acute lymphoblastic leukemia
por: Cassaro, Adriana, et al.
Publicado: (2021)

The Properties of Normal Conducting Cathodes in FZD Superconducting Gun
por: Xiang, R, et al.
Publicado: (2009)

Antitumor effect and mechanism of FZD7 polypeptide vaccine
por: Hua, Zhongke, et al.
Publicado: (2022)

GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling
por: Wang, Liang, et al.
Publicado: (2022)

Robust Colonic Epithelial Regeneration and Amelioration of Colitis via FZD-Specific Activation of Wnt Signaling
por: Xie, Liqin, et al.
Publicado: (2022)

Knockdown of circEXOC6 inhibits cell progression and glycolysis by sponging miR-433-3p and mediating FZD6 in glioma
por: Deng, Yu, et al.
Publicado: (2023)

MiR-199a Regulates Cell Proliferation and Survival by Targeting FZD7
por: Song, Jiugang, et al.
Publicado: (2014)

RNF43 R117fs mutant positively regulates Wnt/β-catenin signaling by failing to internalize FZD expressed on the cell surface
por: Cho, A-Ri, et al.
Publicado: (2022)

Regulatory variant in FZD6 gene contributes to nonsyndromic cleft lip and palate in an African-American family
por: Cvjetkovic, Nevena, et al.
Publicado: (2015)

Isolated recessive nail dysplasia caused by FZD6 mutations: report of three families and review of the literature
por: Kasparis, C., et al.
Publicado: (2016)

A novel FZD6 mutation revealed the cause of cleft lip and/or palate in a Chinese family
por: Zhang, Jieni, et al.
Publicado: (2019)

Comprehensive Genomic Analysis for Identifying FZD6 as a Novel Diagnostic Biomarker for Acute Myeloid Leukemia
por: Yang, Li, et al.
Publicado: (2022)

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2
por: Li, Changgong, et al.
Publicado: (2008)

EGFR is required for Wnt9a/Fzd9b signalling specificity in haematopoietic stem cells
por: Grainger, Stephanie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_icedrdk3d352kkt0frbkhoci2v