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Blockade of the Sigma-1 Receptor Relieves Cognitive and Emotional Impairments Associated to Chronic Osteoarthritis Pain

Osteoarthritis is the most common musculoskeletal disease worldwide, often characterized by degradation of the articular cartilage, chronic joint pain and disability. Cognitive dysfunction, anxiety and depression are common comorbidities that impact the quality of life of these patients. In this stu...

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Detalles Bibliográficos
Autores principales:	Carcolé, Mireia, Zamanillo, Daniel, Merlos, Manuel, Fernández-Pastor, Begoña, Cabañero, David, Maldonado, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510262/ https://www.ncbi.nlm.nih.gov/pubmed/31130863 http://dx.doi.org/10.3389/fphar.2019.00468

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