How to Conduct Clinical Trials in Children: A Tutorial

Despite a growing interest in, and commitment to, implementing pediatric clinical trials, approximately one in every five trials in children fails because of inappropriate study design, suboptimal experiment planning, or inadequate participant enrollment. This tutorial, presented from the perspectiv...

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Detalles Bibliográficos
Autores principales: Shakhnovich, Valentina, Hornik, Christoph P., Kearns, Gregory L., Weigel, Jaylene, Abdel‐Rahman, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Tutorials
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510379/
https://www.ncbi.nlm.nih.gov/pubmed/30657253
http://dx.doi.org/10.1111/cts.12615
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author Shakhnovich, Valentina
Hornik, Christoph P.
Kearns, Gregory L.
Weigel, Jaylene
Abdel‐Rahman, Susan M.
author_facet Shakhnovich, Valentina
Hornik, Christoph P.
Kearns, Gregory L.
Weigel, Jaylene
Abdel‐Rahman, Susan M.
author_sort Shakhnovich, Valentina
collection PubMed
description Despite a growing interest in, and commitment to, implementing pediatric clinical trials, approximately one in every five trials in children fails because of inappropriate study design, suboptimal experiment planning, or inadequate participant enrollment. This tutorial, presented from the perspectives of seasoned pediatric investigators, an experienced research coordinator, and an established pediatric clinical trials network, is designed to provide practical guidance for successfully implementing pediatric clinical trials at an academic center or another comparable institution.
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spelling pubmed-65103792019-05-20 How to Conduct Clinical Trials in Children: A Tutorial Shakhnovich, Valentina Hornik, Christoph P. Kearns, Gregory L. Weigel, Jaylene Abdel‐Rahman, Susan M. Clin Transl Sci Tutorials Despite a growing interest in, and commitment to, implementing pediatric clinical trials, approximately one in every five trials in children fails because of inappropriate study design, suboptimal experiment planning, or inadequate participant enrollment. This tutorial, presented from the perspectives of seasoned pediatric investigators, an experienced research coordinator, and an established pediatric clinical trials network, is designed to provide practical guidance for successfully implementing pediatric clinical trials at an academic center or another comparable institution. John Wiley and Sons Inc. 2019-03-18 2019-05 /pmc/articles/PMC6510379/ /pubmed/30657253 http://dx.doi.org/10.1111/cts.12615 Text en © 2019 The Authors. Clinical and Translational Science published by Wiley Periodicals, Inc. on behalf of the American Society for Clinical Pharmacology and Therapeutics. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Tutorials
Shakhnovich, Valentina
Hornik, Christoph P.
Kearns, Gregory L.
Weigel, Jaylene
Abdel‐Rahman, Susan M.
How to Conduct Clinical Trials in Children: A Tutorial
title How to Conduct Clinical Trials in Children: A Tutorial
title_full How to Conduct Clinical Trials in Children: A Tutorial
title_fullStr How to Conduct Clinical Trials in Children: A Tutorial
title_full_unstemmed How to Conduct Clinical Trials in Children: A Tutorial
title_short How to Conduct Clinical Trials in Children: A Tutorial
title_sort how to conduct clinical trials in children: a tutorial
topic Tutorials
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510379/
https://www.ncbi.nlm.nih.gov/pubmed/30657253
http://dx.doi.org/10.1111/cts.12615
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