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Assessment of tumor mutation burden calculation from gene panel sequencing data

Background: High tumor mutation burden (TMB) is an emerging selection biomarker for immune checkpoint blockade in tumors such as melanoma and non-small cell lung cancer. TMB is typically calculated from whole genome sequencing or whole exome sequencing (WES) data. Recently, clinical trials showed th...

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Detalles Bibliográficos
Autores principales:	Xu, Zhenwu, Dai, Jiawei, Wang, Dandan, Lu, Hui, Dai, Heng, Ye, Hao, Gu, Jianlei, Chen, Shengjia, Huang, Bingding
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510391/ https://www.ncbi.nlm.nih.gov/pubmed/31123404 http://dx.doi.org/10.2147/OTT.S196638

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